Best branched amino acids contraindications
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The proteins we ingest undergo a first digestion in the stomach, by pepsin, which leads to the breakdown of the peptide bond. Once in the small intestine, the already partially digested proteins are further broken down by pancreatic juice and enteric juice. Thus the proteins are broken down up to the amino acids which are then absorbed by active transport, which differs according to the type of amino acid; for some, for example, the presence of vitamin B6 is necessary.
By ingesting a supplement based on amino acids, their absorption is immediately passed, so after reaching the liver, they are redistributed to the general circulation and can be used for the synthesis of new tissue proteins, the synthesis of plasma proteins, used to be inserted into the pathway. metabolic of lipids or be used for energy production.
If amino acids are not used for protein synthesis, they are oxidized directly or transformed into glycides and lipids.
In both cases, the body must remove the amino group and carry out this operation through processes that take the name of amino acid desamination (hydrolytic, oxidative and reductive desamination), transamination (transport of the amino group by specific transaminases) and decarboxylation (transformation of amino acids into primary amines).
The dissolution of the amino group leads to the creation of ammonia which is then released by the body, partly through the urine, partly through its transformation in the liver into urea, which in turn is always eliminated in the urine.
Now if you have read so far it is clear that an excessive ingestion of branched chain amino acids leads to a surplus of work for the liver and kidneys.
It is no coincidence that many of the first symptoms, in the case of high ingestion of branched chain amino acids, are the enlarged fig, and then, in the most extreme cases, pass to renal failure.
This says science (I have also summarized a lot ...), for this reason my advice is always to be accompanied by a good sports doctor and / or dietician who, based on the training load and the dietary regime, will proceed to determine the correct amount of branched chain amino acids to be taken.
N.B .: the photo is purely indicative